in

NHS in talks to buy DIY home coronavirus tests after Government row

The UK is looking at rolling out DIY coronavirus home testing kits after ministers were accused of allowing thousands of infected people to walk the streets undiagnosed.

Britain’s chief scientific adviser revealed the Government was reviewing the ‘easy to use’ blood tests which analyse antibodies in the body and give a diagnosis in hours.

They would be a huge improvement on the current nasal swabs used by the NHS, which take up to 48 hours to produce results and leave suspected patients in limbo. 

The tests – known as serological tests which will presumably be free on the NHS – can also detect asymptomatic patients and those who have already beat the bug. 

But Sir Patrick Vallance warned it could be weeks or months before the kits are rolled out because health bosses are not confident they are reliable enough.

The delay will prompt more fury because other countries around the world have been using testing kits that rapidly produce results.

A finer prick test that takes just minutes to give a diagnosis has been used in China, South Korea, Japan and Italy.

The UK has been criticised for potentially allowing tens of thousands of patients to go undiagnosed due to a lack of testing. Here, a medic tests a patient at a drive through screening centre in New Jersey

The UK has been criticised for potentially allowing tens of thousands of patients to go undiagnosed due to a lack of testing. Here, a medic tests a patient at a drive through screening centre in New Jersey

Britain's chief scientific adviser Sir Patrick Vallance (pictured) revealed the Government was reviewing the 'easy to use' blood tests which analyse antibodies in the body and give a diagnosis in hours

Britain’s chief scientific adviser Sir Patrick Vallance (pictured) revealed the Government was reviewing the ‘easy to use’ blood tests which analyse antibodies in the body and give a diagnosis in hours 

SureScreen Diagnostics says it has developed a finger prick test that takes just 10 minutes to give a diagnosis and is correct 98 per cent of the time

Finger prick tests like SureScreen Diagnostics’ device have already been used in other countries and take just minutes to give a diagnosis. Although there is a question about how reliable they are

It comes after the UK death toll jumped to 137 and infections climbed to 2,695 – although experts say the true infection rate is likely more than 80,000. 

Sir Patrick told a press briefing in London today: ‘Everyone’s looking for a serological test. They’ve got some in some parts of the world. 

‘There are two types, one that requires a laboratory testing and the other is an easy to use thing that you can use yourself at home. 

Row over testing

WHAT IS THE UK DOING NOW?

Around 5,000 tests are being carried out a day. 

Those are mostly patients who are already in hospital. 

Some 100 GP surgeries have agreed to carry out tests on patients, as part of surveillance to asses the prevalence. 

However, those who feel they have symptoms are being told to self-isolate without being routinely tested.

WHAT IS THE UK GOING TO DO?

Boris Johnson has vowed to increase tests to 25,000 a day, although he did not give a timescale.

He also said that health workers will be prioritised. Many have complained that they are being forced to stop work as they are unsure whether or not they have the disease.

WHAT DO THE EXPERTS SAY?

The message from the World Health Organisation is ‘test test test’, to avoid trying to fight an outbreak ‘blindfolded’. South Korea says it has got on top of an outbreak with stringent testing. 

‘Currently we’re looking at both of those, but you’ve clearly got to have reliability. That’s the first thing. There’s a danger that you have something that isn’t reliable enough.’

Sir Patrick added the tests were being worked up ‘as we speak’.

He said: ‘If you can get to mass testing, which would definitely be the idea, then that does become very useful.

‘It answers the question of what proportion of patients are asymptomatic, a really important unknown in this. 

‘Secondly it can tell you who’s had it and developed an antibody against it and therefore won’t catch it again.’

The tests would first be used on healthcare workers, who are essential in the fight against the virus. 

Sir Patrick added: ‘That then becomes important in understanding who’s safe to go back and start working. Gives much greater flexibility in terms of the NHS.’ 

‘We shouldn’t dream that you can scale up hundreds of thousands of tests in a day. You can’t… it doesn’t happen overnight. It won’t be in a few days.’

Speaking tonight at the Prime Minister’s daily coronavirus press briefing this evening, Chief Medical Officer Chris Whitty said he was not confident the current serological tests on the market were reliable enough.

But he assured the public that in time there will be one accurate enough to be rolled out and said they will help ‘society normalise little by little’. 

Dr Martin Marshall, the chair of the Royal College of GPs, said there is a 'shortage of available testing kits' in the UKD

Dr Martin Marshall, the chair of the Royal College of GPs, said there is a ‘shortage of available testing kits’ in the UKD

Why does UK have a shortage of testing kits when Tennessee can fly in 500,000 from Italy? 

The UK has a shortage of coronavirus tests, one of the country’s most senior doctors admitted today.

Dr Martin Marshall, chair of the Royal College of GPs, warned there are not enough testing kits to go around in Britain. 

For the past five days the UK has tested, on average, 3,700 people each day – a total the Government’s chief scientific adviser has accepted is ‘clearly not enough’.

Meanwhile, the US state of Tennessee – which has a population 10 times smaller than the UK – yesterday took delivery of 500,000 kits.

British officials have refused to reveal how many tests are on hand for NHS patients but a supply the size of Tennessee’s could last for months at the current rate of testing.

NHS staff across the country are crying out to be tested so they can be sure they’re safe to work around patients and an online petition calling for this to happen has been signed by almost a million people.

Speaking to Sky News, Dr Marshall said: ‘At the moment there is a shortage of available testing kits for the conventional test that’s currently being used. Hopefully that will improve over the next few weeks.’ 

The home tests work by picking up on antibodies, the immune system’s defence mechanism, that fight coronavirus. 

Those with antibodies that react to the killer bug will have already had it and recovered without knowing, and are likely to be immune to reinfection. 

Around 5,000 tests are being carried out a day in Britain, but they are mostly reserved for patients who are already in hospital. 

Some 100 GP surgeries have agreed to carry out tests on patients, as part of surveillance to asses the prevalence. 

However, those who feel they have symptoms are being told to self-isolate without being routinely tested.

Boris Johnson has vowed to increase tests to 25,000 a day, although he did not give a timescale.

He also said that health workers will be prioritised. Many have complained that they are being forced to stop work as they are unsure whether or not they have the disease.

The message from the World Health Organisation is ‘test test test’, to avoid trying to fight an outbreak ‘blindfolded’. South Korea says it has got on top of an outbreak with stringent testing. 

One of Britain’s most senior doctors admitted today the UK has a shortage of coronavirus tests, 

Dr Martin Marshall, chair of the Royal College of GPs, warned there are not enough testing kits to go around in Britain.

It comes after Prime Minister Boris Johnson yesterday promised he would ramp up the number of people who are getting swabbed for the virus to 25,000 a day.

For the past five days the UK has tested, on average, 3,700 people each day – a total the Government’s chief scientific adviser has accepted is ‘clearly not enough’.

The UK's coronavirus outbreak has spiralled out of control and London is at the centre of an epidemic of thousands or tens of thousands of infected people. Around 900 people in the city have been officially diagnosed (Pictured, central London was bereft of traffic this morning)

The UK’s coronavirus outbreak has spiralled out of control and London is at the centre of an epidemic of thousands or tens of thousands of infected people. Around 900 people in the city have been officially diagnosed (Pictured, central London was bereft of traffic this morning)

Sainsbury's in Northwich, Cheshire, opened early for pensioners today so they could do their shopping before the shelves get ransacked. As shoppers continue to panic buy

Sainsbury’s in Northwich, Cheshire, opened early for pensioners today so they could do their shopping before the shelves get ransacked

Some of the holidaymakers who had been trapped on the Braemar cruise ship in Cuba are pictured walking home through Heathrow Airport this morning after flying home

Some of the holidaymakers who had been trapped on the Braemar cruise ship in Cuba are pictured walking home through Heathrow Airport this morning after flying home

TESTING STOPPED THE VIRUS IN A SMALL ITALIAN TOWN 

Italian authorities have managed to contain the killer coronavirus outbreak in a small town near Venice through a rigorous testing strategy.

Health bosses in Vò – 45miles (72km) east of the tourist hotspot – have had no new cases for 48 hours.

Officials conducted an experiment in the town, which is home to 3,300 people, to test and re-test all inhabitants.

The Financial Times reports the strategy meant everyone would be tested – even if they showed no symptoms.

Andrea Crisanti, an infectious disease specialist taking part in the experiment, told the newspaper the method allowed officials to get the clearest picture about the size of the outbreak.

The experiment began at the end of February, and the initial roll-out of tests showed around three per cent of patients were infected.

This dropped ten-fold when the second testing round was carried out 10 days later, after quarantining all of the infected and their contacts.

Professor Crisanti, who is on a sabbatical at the University of Padua, said: ‘In the UK, there are a whole lot of infections that are completely ignored.

‘We were able to contain the outbreak [in Vò] because we identified and eliminated the ‘submerged’ infections and isolated them. This is what makes the difference.

Meanwhile, the US state of Tennessee – which has a population 10 times smaller than the UK – yesterday took delivery of 500,000 kits.

British officials have refused to reveal how many tests are on hand for NHS patients but a supply the size of Tennessee’s could last for months at the current rate of testing.

NHS staff across the country are crying out to be tested so they can be sure they’re safe to work around patients and an online petition calling for this to happen has been signed by almost a million people.

Speaking to Sky News, Dr Marshall said: ‘At the moment there is a shortage of available testing kits for the conventional test that’s currently being used. Hopefully that will improve over the next few weeks.’

Dr Marshall and the Royal College of GPs (RCGP) are calling for NHS staff to be tested as routine to make sure they don’t have to take time off work unless they’re definitely ill.

Health service staff numbers dropping is a major fear for officials dealing with the epidemic.

It would make the impact of the coronavirus considerably worse because hospitals would be totally overwhelmed and unable to care for patients.

For this reason schools are being kept open for the children of NHS staff and recently retired employees are being allowed to return to work.

Dr Marshall added: ‘Routine testing of health professional staff isn’t available…

‘This should be a priority because there are a lot of my colleagues who are at home unable to work or perhaps only able to work on the telephone when they really want to be out there supporting their teams.

‘They’re doing that because they simply don’t know whether they’ve got the virus.’

MailOnline looks at the cutting-edge testing kits currently being rolled out in other counties and at private clinics in Britain

FINGER PRINT TEST

Name: COVID-19 IgM IgG Rapid Test

Manufacturers: BioMedomics

Diagnostic time: 15 minutes 

The blood test is not being used in the UK, despite health bodies in China, Italy and Japan diagnosing patients with it.

On March 5, BioMedomics claimed its ‘quick and easy’ test was ready and being used in South Korea, Japan, Italy, China and some countries in the Middle East. 

After the sample of blood is collected, a technician injects it into the analysis device – which is about the size of an Apple TV or Roku remote – along with some buffer, and waits 15 minutes.

One line means negative, two lines in a spread-out configuration means the sample contains antibodies that the body starts making shortly after infection.

BioMedomics claims its test can screen for coronavirus in 15 minutes using a small drop of blood and a tiny device that can be carried into the field

BioMedomics claims its test can screen for coronavirus in 15 minutes using a small drop of blood and a tiny device that can be carried into the field

A blood sample is collected, inserted into the reader, a buffer is combined, and results come back within 15 minutes, the company claims

A blood sample is collected, inserted into the reader, a buffer is combined, and results come back within 15 minutes, the company claims 

Two lines closer together mean the person is positive for the later-stage antibodies, and three lines mean the patient is positive for both types of antibodies.  

A small study showed the test produced a correct response 80 per cent of the time.

PHE confirmed it was not using the advanced blood test because it was not accurate enough, and are hoping to develop their own. The US Food and Drug Administration (FDA) is also yet to approve it. 

A former PHE strategist said he was ‘not confident’ the test could produce correct results and is therefore unlikely to be rolled out. However, the method was desirable. 

NASAL SWAB

Name: TaqPath COVID-19 Combo Kit 

Manufacturers: ThermoFisher

Diagnostic time: Four hours 

The DIY test detects specific DNA given off by the coronavirus in the noses of infected patients.

Two men wearing suits were pictured carrying a box from ThermoFisher – which makes coronavirus tests that give results in four hours – outside Downing Street last night

Two men wearing suits were pictured carrying a box from ThermoFisher – which makes coronavirus tests that give results in four hours – outside Downing Street last night

Samples are then delivered to labs where they are analysed and results are produced within four hours.

The test was approved by the US Food and Drug Administration this week and 5million kits will be sent across America in the coming days.

It is hoped the UK will follow suit after representatives from ThermoFisher, based in Waltham, Massachusetts, were seen entering Downing Street last night carrying a box with the tests. 

It is understood ministers were giving a demonstration of how the test works.

FINGER PRICK TEST

Name: COVID-19 Rapid Test Cassette 

Manufacturers: SureScreen Diagnostics

Diagnostic time: Ten minutes 

The private firm, based in Derby, has created a test which can allegedly determine with 98 per cent certainty if a person is infected. 

It involves taking a blood sample via finger prick and then putting it into a screening device.

SureScreen Diagnostics says a prick of blood from the fingertip is sufficient to determine with more than 98 per cent accuracy

SureScreen Diagnostics says a prick of blood from the fingertip is sufficient to determine with more than 98 per cent accuracy

The private firm says its test has been validated and is already being used in the Germany, Spain, Switzerland, Netherlands, Turkey, UAE, Kuwait and Oman

The private firm says its test has been validated and is already being used in the UK, Ireland, Germany, Spain, Switzerland, Netherlands, Turkey, UAE, Kuwait and Oman. Currently, official swap-based methods take between 24 and 48 hours for results to come back

Users then put their blood sample in a screening device and results are displayed in a similar fashion to an at-home pregnancy test within minutes

Public Health England cautions members of the public against using such tests amid fears they are unreliable, saying there is ‘little information on the accuracy of the tests’

Row over testing

WHAT IS THE UK DOING NOW?

Around 5,000 tests are being carried out a day. 

Those are mostly patients who are already in hospital. 

Some 100 GP surgeries have agreed to carry out tests on patients, as part of surveillance to asses the prevalence. 

However, those who feel they have symptoms are being told to self-isolate without being routinely tested.

WHAT IS THE UK GOING TO DO?

Boris Johnson has vowed to increase tests to 25,000 a day, although he did not give a timescale.

He also said that health workers will be prioritised. Many have complained that they are being forced to stop work as they are unsure whether or not they have the disease.

WHAT DO THE EXPERTS SAY?

The message from the World Health Organisation is ‘test test test’, to avoid trying to fight an outbreak ‘blindfolded’. South Korea says it has got on top of an outbreak with stringent testing. 

Results are displayed in a similar fashion to those of an at-home pregnancy test within minutes and could potentially save delays in diagnosis. 

SureScreen says its test has been validated and is already being used by private buyers in the UK, Ireland, Germany, Spain, Switzerland, Netherlands, Turkey, UAE, Kuwait and Oman. 

It is believed around 175,000 tests have been conducted with the SureScreen kit so far. The company claims it has had over two million orders for next month. 

Director David Campbell said: ‘We’ve been working hard to produce a coronavirus test (COVID19) that can be used at the patient side, with capillary blood, easily taken from someone’s fingertip and diagnose them within 10 minutes.

‘There is a big problem with the diagnosis of the disease currently because the standard method of screening is to send samples to the laboratory, which takes a lot of time. 

‘Meanwhile, someone could be spreading the virus without knowing, or having the issue of self-isolation.’  

FACE MASK TESTS

Manufacturers: University of Leicester

Diagnostic time: 12 hours

How it works: Breath test inserted in a mask

Scientists have started a trial of the pioneering £2 gadget, which tests have already proven can detect tuberculosis, a deadly lung infection.

Scientists have started a trial of the pioneering £2 gadget (pictured), which tests have already proven can detect tuberculosis

Scientists have started a trial of the pioneering £2 gadget (pictured), which tests have already proven can detect tuberculosis

The researchers at the University of Leicester and the University of Pretoria designed 3D printed strips of polyvinyl alcohol that are inserted into the mask (pictured)

The researchers at the University of Leicester and the University of Pretoria designed 3D printed strips of polyvinyl alcohol that are inserted into the mask (pictured)

The masks, which could cost pennies if manufactured on a wider scale, are fitted with strips that soak up droplets from the wearer’s breath, which may be carrying traces of bacterial or viral infection.

The strips can be tested in labs with results coming back within hours. Current tests for coronavirus can take up to 48 hours. 

University of Leicester researchers believe it will be at least two months before they can test the masks on actual COVID-19 patients.

But they are hopeful it will work because it is a respiratory disease, meaning it infects the lungs and can is present in the air people breathe out.  

After 30 minutes, the strips can be tested in a laboratory (pictured)

After 30 minutes, the strips can be tested in a laboratory (pictured)

First, the team have to test the gadgets on dozens of patients with other lung infections to prove they can pick up bugs other than tuberculosis, which they were designed for.

Patients with infections such as flu and bronchitis will have the results from their mask tests compared to those from throat swabs, which are known to be accurate. 

Tests on tuberculosis patients, the only ones that have been done so far, show the masks can detect the killer disease almost 90 per cent of the time.

Leicester’s Professor Mike Barer and colleagues are hopeful they will be successful because the coronavirus infects the lungs in a similar way to tuberculosis.

BREATH TEST 

Manufacturers: Northumbria University, Newcastle

Diagnostic time: Almost instantly 

A breath test that helps rapidly identify patients with coronavirus has been developed by British scientists.

The technology, developed by a team at Northumbria University in Newcastle, is still in development and needs further testing.

But experts believe it could be quickly change the way the virus is spotted around the world. 

A breath test that helps rapidly identify patients with coronavirus has been developed by British scientists (file)

A breath test that helps rapidly identify patients with coronavirus has been developed by British scientists (file)

Dr Sterghios Moschos, right, said the test could be used to produce results in minutes

Dr Sterghios Moschos, right, said the test could be used to produce results in minutes

The Northumbria team’s test collects breath samples which can be tested separately for biological information – known as biomarkers.

These biomarkers, which include DNA, RNA, proteins and fat molecules, can spot diseases of the lung and other parts of the body.

People simply breath into the device, which is similar to a breathalyser used by the police.

Dr Sterghios Moschos, associate professor at Northumbria University, said: ‘Our ambition is to reduce the need for bloodletting for diagnosis in its broadest sense.’ 

The test is currently being trialled.  

PRIVATE HARLEY STREET CLINIC

Manufacturers: Private Harley Street Clinic

Diagnostic time: Three days

How it works: Nose and throat swab

Price: £375  

More than 2,000 people have ordered a £375 home testing kit from a Harley Street clinic in London after being turned down by the NHS, according to the Daily Telegraph.

In addition to individuals, some 60 firms including oil and telecoms companies, have bought them for their staff. 

On its website, the item can be easily 'added to cart,' much in the same way as conventional online products

On its website, the item can be easily ‘added to cart,’ much in the same way as conventional online products

Dr Mark Ali, director of the Private Harley Street Clinic on London's world-renowned medical avenue, said his practice was offering a new kit for £375 each

Dr Mark Ali, director of the Private Harley Street Clinic on London’s world-renowned medical avenue, said his practice was offering a new kit for £375 each

The test is posted to the client’s home or preferred address, where the client takes swabs from both the nostrils and throat. 

The sample is then placed in the box provided and posted back as per the instructions. 

Dr Mark Ali, director of the Private Harley Street Clinic on London’s world-renowned medical avenue, said his practice was offering a new kit for £375 each.

On its website, the item can be easily ‘added to cart,’ much in the same way as conventional online products.

The practice says the test is ‘performed by a world renown UKAS accredited British laboratory and the test results are 100% accurate and do not require further tests to confirm any diagnoses.’

The website hastens to add, that though it oversees the entire process, patients should not attempt to pick up their kits from Harley Street.

‘Please note under no circumstances can this test be done in our clinic or be collected from our clinic.’ The website states.

‘It is sent to your designated address by courier service within 48 hrs. Please refer to the details below and order through the link at the bottom of this page.’

Dr Ali told The Telegraph he has received countless requests from buyers.

‘People are worried sick. They want to get some clarity back in their lives,’ he told The Telegraph. 

‘We’ve got university students in England who want to go back to Nepal, but need to know if they have the disease so they can be let back into their own country.

‘We’ve got a businessman who owns a construction company employing 60 people. He needs to know the state of play, or he risks letting down his customers. So every single person in that company is being tested.’ 

CT SCANS

Who came up with the idea? Mount Sinai Health System, New York

Diagnostic time: 1 hour 30 minutes

How it works: Detects lung damage  

Doctors from The Mount Sinai Health System in New York say CT scans may be faster than nasal and throat swabs at diagnosing coronavirus patients. 

The team were the first in the US to analyze lung scans of patients in China with the highly contagious disease.   

They said they were able to identify specific patterns in the lungs as markers of the virus, also known as COVID-19, as it developed over the course of about two weeks>

Patients who received scans zero to two days after symptoms first appeared had little to no evidence of lung disease in their results like this 19-year-old male who had a CT scan one day after symptoms first appeared

Patients who received scans zero to two days after symptoms first appeared had little to no evidence of lung disease in their results like this 19-year-old male who had a CT scan one day after symptoms first appeared

The team said the pattern in the lung of coronavirus patients are similar to scans of patients with SARS and very different from diseases such as bacterial pneumonia (pictured)

The team said the pattern in the lung of coronavirus patients are similar to scans of patients with SARS and very different from diseases such as bacterial pneumonia (pictured)

The researchers say these quicker diagnoses could help keep patients isolated in early stages of the disease, perhaps even before symptoms appear and when it may not show up on other scans such as chest X-rays. 

‘CT scans are an extremely powerful diagnostic tool, because you can seen the inner organs in a three-dimensional way,’ lead author Dr Adam Bernheim, an assistant professor of diagnostic, molecular and interventional radiology at the Icahn School of Medicine at Mount Sinai, told DailyMail.com.

‘And you can see the manifestation of many diseases.’ 

For the study, published in the journal Radiology, the team analyzed scans of 94 patients at four medical centers in four Chinese provinces.

The patients had been admitted between January 18 and February 2, and all had either recently traveled to Wuhan – the epicenter of an outbreak – or had come into contact with an infected person.

Radiologists reviewed the scan and took notes based on when symptoms first appeared and when the CT scan was performed.

Thirty-six patients received scans zero to two days after reporting symptoms and more than half showed no evidence of lung disease.

The team says this is important because it suggests that CT scans cannot reliably detect coronavirus in its very earliest stages.

Nasal and throat swabs test can identify patients even before patients become symptomatic, although some may still have the virus if they first test negative. 

Its results, however, may take days to get back from the agency’s labs.

But 33 patients who received scans three to five days after symptoms developed had patterns of ‘ground glass opacities,’ or haziness in the lungs.

‘The lung abnormalities are very round in shape and affect the perimeter of the lung,’ co-author Dr Michael Chung, an assistant professor of diagnostic, molecular and interventional radiology at the Icahn School of Medicine at Mount Sinai, told DailyMail.com.  

WHAT DO WE KNOW ABOUT THE CORONAVIRUS?

What is the coronavirus? 

A coronavirus is a type of virus which can cause illness in animals and people. Viruses break into cells inside their host and use them to reproduce itself and disrupt the body’s normal functions. Coronaviruses are named after the Latin word ‘corona’, which means crown, because they are encased by a spiked shell which resembles a royal crown.

The coronavirus from Wuhan is one which has never been seen before this outbreak. It has been named SARS-CoV-2 by the International Committee on Taxonomy of Viruses. The name stands for Severe Acute Respiratory Syndrome coronavirus 2.

Experts say the bug, which has killed around one in 50 patients since the outbreak began in December, is a ‘sister’ of the SARS illness which hit China in 2002, so has been named after it.

The disease that the virus causes has been named COVID-19, which stands for coronavirus disease 2019.

Dr Helena Maier, from the Pirbright Institute, said: ‘Coronaviruses are a family of viruses that infect a wide range of different species including humans, cattle, pigs, chickens, dogs, cats and wild animals. 

‘Until this new coronavirus was identified, there were only six different coronaviruses known to infect humans. Four of these cause a mild common cold-type illness, but since 2002 there has been the emergence of two new coronaviruses that can infect humans and result in more severe disease (Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) coronaviruses). 

‘Coronaviruses are known to be able to occasionally jump from one species to another and that is what happened in the case of SARS, MERS and the new coronavirus. The animal origin of the new coronavirus is not yet known.’ 

The first human cases were publicly reported from the Chinese city of Wuhan, where approximately 11million people live, after medics first started publicly reporting infections on December 31.

By January 8, 59 suspected cases had been reported and seven people were in critical condition. Tests were developed for the new virus and recorded cases started to surge.

The first person died that week and, by January 16, two were dead and 41 cases were confirmed. The next day, scientists predicted that 1,700 people had become infected, possibly up to 7,000. 

Where does the virus come from?

According to scientists, the virus almost certainly came from bats. Coronaviruses in general tend to originate in animals – the similar SARS and MERS viruses are believed to have originated in civet cats and camels, respectively.

The first cases of COVID-19 came from people visiting or working in a live animal market in Wuhan, which has since been closed down for investigation.

Although the market is officially a seafood market, other dead and living animals were being sold there, including wolf cubs, salamanders, snakes, peacocks, porcupines and camel meat. 

A study by the Wuhan Institute of Virology, published in February 2020 in the scientific journal Nature, found that the genetic make-up virus samples found in patients in China is 96 per cent identical to a coronavirus they found in bats.

However, there were not many bats at the market so scientists say it was likely there was an animal which acted as a middle-man, contracting it from a bat before then transmitting it to a human. It has not yet been confirmed what type of animal this was.

Dr Michael Skinner, a virologist at Imperial College London, was not involved with the research but said: ‘The discovery definitely places the origin of nCoV in bats in China.

‘We still do not know whether another species served as an intermediate host to amplify the virus, and possibly even to bring it to the market, nor what species that host might have been.’  

So far the fatalities are quite low. Why are health experts so worried about it? 

Experts say the international community is concerned about the virus because so little is known about it and it appears to be spreading quickly.

It is similar to SARS, which infected 8,000 people and killed nearly 800 in an outbreak in Asia in 2003, in that it is a type of coronavirus which infects humans’ lungs. It is less deadly than SARS, however, which killed around one in 10 people, compared to approximately one in 50 for COVID-19.

Another reason for concern is that nobody has any immunity to the virus because they’ve never encountered it before. This means it may be able to cause more damage than viruses we come across often, like the flu or common cold.

Speaking at a briefing in January, Oxford University professor, Dr Peter Horby, said: ‘Novel viruses can spread much faster through the population than viruses which circulate all the time because we have no immunity to them.

‘Most seasonal flu viruses have a case fatality rate of less than one in 1,000 people. Here we’re talking about a virus where we don’t understand fully the severity spectrum but it’s possible the case fatality rate could be as high as two per cent.’

If the death rate is truly two per cent, that means two out of every 100 patients who get it will die. 

‘My feeling is it’s lower,’ Dr Horby added. ‘We’re probably missing this iceberg of milder cases. But that’s the current circumstance we’re in.

‘Two per cent case fatality rate is comparable to the Spanish Flu pandemic in 1918 so it is a significant concern globally.’

How does the virus spread?

The illness can spread between people just through coughs and sneezes, making it an extremely contagious infection. And it may also spread even before someone has symptoms.

It is believed to travel in the saliva and even through water in the eyes, therefore close contact, kissing, and sharing cutlery or utensils are all risky. It can also live on surfaces, such as plastic and steel, for up to 72 hours, meaning people can catch it by touching contaminated surfaces.

Originally, people were thought to be catching it from a live animal market in Wuhan city. But cases soon began to emerge in people who had never been there, which forced medics to realise it was spreading from person to person. 

What does the virus do to you? What are the symptoms?

Once someone has caught the COVID-19 virus it may take between two and 14 days, or even longer, for them to show any symptoms – but they may still be contagious during this time.

If and when they do become ill, typical signs include a runny nose, a cough, sore throat and a fever (high temperature). The vast majority of patients will recover from these without any issues, and many will need no medical help at all.

In a small group of patients, who seem mainly to be the elderly or those with long-term illnesses, it can lead to pneumonia. Pneumonia is an infection in which the insides of the lungs swell up and fill with fluid. It makes it increasingly difficult to breathe and, if left untreated, can be fatal and suffocate people.

Figures are showing that young children do not seem to be particularly badly affected by the virus, which they say is peculiar considering their susceptibility to flu, but it is not clear why. 

What have genetic tests revealed about the virus? 

Scientists in China have recorded the genetic sequences of around 19 strains of the virus and released them to experts working around the world. 

This allows others to study them, develop tests and potentially look into treating the illness they cause.   

Examinations have revealed the coronavirus did not change much – changing is known as mutating – much during the early stages of its spread.

However, the director-general of China’s Center for Disease Control and Prevention, Gao Fu, said the virus was mutating and adapting as it spread through people.

This means efforts to study the virus and to potentially control it may be made extra difficult because the virus might look different every time scientists analyse it.   

More study may be able to reveal whether the virus first infected a small number of people then change and spread from them, or whether there were various versions of the virus coming from animals which have developed separately.

How dangerous is the virus?  

The virus has a death rate of around two per cent. This is a similar death rate to the Spanish Flu outbreak which, in 1918, went on to kill around 50million people.

Experts have been conflicted since the beginning of the outbreak about whether the true number of people who are infected is significantly higher than the official numbers of recorded cases. Some people are expected to have such mild symptoms that they never even realise they are ill unless they’re tested, so only the more serious cases get discovered, making the death toll seem higher than it really is.

However, an investigation into government surveillance in China said it had found no reason to believe this was true.

Dr Bruce Aylward, a World Health Organization official who went on a mission to China, said there was no evidence that figures were only showing the tip of the iceberg, and said recording appeared to be accurate, Stat News reported.

Can the virus be cured? 

The COVID-19 virus cannot be cured and it is proving difficult to contain.

Antibiotics do not work against viruses, so they are out of the question. Antiviral drugs can work, but the process of understanding a virus then developing and producing drugs to treat it would take years and huge amounts of money.

No vaccine exists for the coronavirus yet and it’s not likely one will be developed in time to be of any use in this outbreak, for similar reasons to the above.

The National Institutes of Health in the US, and Baylor University in Waco, Texas, say they are working on a vaccine based on what they know about coronaviruses in general, using information from the SARS outbreak. But this may take a year or more to develop, according to Pharmaceutical Technology.

Currently, governments and health authorities are working to contain the virus and to care for patients who are sick and stop them infecting other people.

People who catch the illness are being quarantined in hospitals, where their symptoms can be treated and they will be away from the uninfected public.

And airports around the world are putting in place screening measures such as having doctors on-site, taking people’s temperatures to check for fevers and using thermal screening to spot those who might be ill (infection causes a raised temperature).

However, it can take weeks for symptoms to appear, so there is only a small likelihood that patients will be spotted up in an airport.

Is this outbreak an epidemic or a pandemic?   

The outbreak was declared a pandemic on March 11. A pandemic is defined by the World Health Organization as the ‘worldwide spread of a new disease’. 

Previously, the UN agency said most cases outside of Hubei had been ‘spillover’ from the epicentre, so the disease wasn’t actually spreading actively around the world.

 

Source link

Written by Angle News

Leave a Reply

Christian Bale joins his wife Sibi and son Joseph for a scooter ride through their neighborhood

Pentagon successfully launches tests hypersonic glide body that flies faster than the speed of sound