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The SAGE files: One in 20 Covid-19 patients is infectious after 14 days, report finds

Boris Johnson was warned confusion about the Covid-19 alert level may spark ‘public anxiety’ days before eased lockdown, secret papers published today revealed.

SAGE scientists urged Number 10 to be clear about the threat level of coronavirus in a report submitted to ministers on May 26.

It came two days before the Prime Minister reopened schools, outdoor markets and car showrooms, and told a chunk of the workforce to return to work.

At the time, the coronavirus alert level was at a four, meaning the virus was growing exponentially. Government scientists urged ministers not to ease lockdown until this had come down to level three.

In the SAGE report, scientists said: ‘People need to know what to do at a particular alert level and how to prepare for a change in Alert Level.’

‘If it is not clear what to do when an Alert Level increases, it is expected that levels of public anxiety will increase.’

In a public service announcement that was criticised for being confusing, Mr Johnson told the British public that the UK was currently at level four, but was ‘moving towards level three’.

The SAGE report specifically warned against this kind of mixed-messaging, adding: ‘For clarity of public communications, Alert Levels should be a simple step level system with no sub-division.’

Some 31 documents were today published by the Government Office for Science, which is headed by Sir Patrick Vallance, England’s chief scientific adviser.

The SAGE papers are being released in a bid to show greater transparency from the Government. 

They are among dozens in a tranche of papers presented to SAGE, the Government’s Scientific Advisory Group for Emergencies, over recent months to help guide ministers through the crisis.

And the reports detail all the scientific advice which is being presented to decision-making officials who dictate when and how the country moves out of lockdown.  








Files released today revealed scientists told the Government:

  • As many as one in 20 Covid-19 patients hospitalised with the disease remain infectious after two weeks;
  • The Government’s top experts still don’t know how accurate Covid-19 swab tests are. with some studies suggesting they could miss one in five Covid patients;
  • A YouGov poll on March 17 found more than half (55 per cent) of Brits were still going to bars pubs and restaurants and six in 10 were still seeing family members and friends from other households, despite Government guidance advising not to; 
  • NHS antibody testing scheme suggest 16 per cent of staff have had coronavirus and a FIFTH of hospital patients have recovered from the virus;
  • The Government has been warned since April 20 that taxi drivers and factory workers are among the most at-risk occupations for catching the disease;
  • SAGE experts admitted it still doesn’t know how often the Covid-19 swabs rolled out nationally in the UK give false negatives; 
  • Prisons, migrant centres, long stay mental health hospitals and homeless shelters could be potential Covid-19 breeding grounds in the future;
  • The Government has been told that coronavirus health messages tailored specifically for different ethnic groups are ‘particularly important’.
SAGE scientists urged the Government to be clear about the threat level of coronavirus in a report handed to No 10 on May 26. It came two days before the PM reopened schools, outdoor markets and car showrooms, and told a chunk of the workforce to return to work

SAGE scientists urged the Government to be clear about the threat level of coronavirus in a report handed to No 10 on May 26. It came two days before the PM reopened schools, outdoor markets and car showrooms, and told a chunk of the workforce to return to work

SAGE scientists urged Number 10 to be clear about the threat level of coronavirus in a report submitted to ministers on May 26. It came two days before the Prime Minister reopened schools, outdoor markets and car showrooms, and told a chunk of the workforce to return to work

SAGE scientists urged Number 10 to be clear about the threat level of coronavirus in a report submitted to ministers on May 26. It came two days before the Prime Minister reopened schools, outdoor markets and car showrooms, and told a chunk of the workforce to return to work

One in 20 hospitalised patients may be infectious beyond 14 days 

About 5 per cent of patients ill enough with coronavirus to be admitted to hospital are contagious to others after two weeks, two separate SAGE reports found.

Two teams of Government scientists submitted papers to ministers on May 28 warning some sufferers had high enough viral load to infect others for 20 days. 

They reviewed the available evidence from around the world looking into viral load in hospitalised patients with the disease, as well as new UK research on British patients.

The team of virologists and infectious disease experts – which included Professor Peter Horby, an epidemiologist from Oxford University – found most people are not infectious 12 days after symptoms start. 

Samples from the upper respiratory tract of 74 Covid patients in the UK showed viral load was picked up after 20 days in some patients

Samples from the upper respiratory tract of 74 Covid patients in the UK showed viral load was picked up after 20 days in some patients

‘However, a very small minority of hospitalised individuals might remain infectious until day 20’, they write, adding that many of these patients will be elderly.

They warned that this finding poses a ‘risk for onwards transmission to carers’, care home workers and family members who may then go and pass the disease onto others. 

The scientists recommended that people working in high risk areas like care homes, as well as care home residents themselves, be given swab and antibody tests after recovering from the virus before returning.

A high level of antibodies in the blood ‘is likely to correlate with a low probability of infectiousness’, the researchers say.

Accuracy of coronavirus PCR swab tests is still not fully understood

The swab tests currently being used in the UK to diagnose coronavirus can miss infected people up to a fifth of the time, according to a paper submitted to ministers this month.

The UK’s Covid-19 testing programme uses a network of laboratories to detect SARS-CoV-2 in nasopharyngeal swabs, which take samples from the throat and nose.

SAGE researchers said these swabs – the gold standard of testing currently- are 95 per cent sensitive and specific.

This means that, under laboratory settings, they are correct more than nine times out of 10.  

But errors in the way samples are collected in the community and transported to laboratories can bring down their accuracy significantly. 

A model used by SAGE scientists shows the likelihood of a swab giving a false negative is lowest between day five and day 10 of infection of symptoms

A model used by SAGE scientists shows the likelihood of a swab giving a false negative is lowest between day five and day 10 of infection of symptoms

Coronavirus death rate is TWICE as high among factory workers and security guards than doctors and nurses, shock data reveals 

Men working in factories or as security guards were twice as likely to die of coronavirus than healthcare workers during the height of the outbreak in Britain, shocking data revealed today.

Office for National Statistics (ONS) experts analysed the occupations of all the 4,700 Covid-19 victims in England and Wales who were of working age (20-64) and died between March 9 and May 25. 

Analysis showed 74 male security guards or bouncers died for every 100,000 men during the brunt of the crisis, followed by a rate of 73 for male factory workers. 

In comparison, male nurses and doctors – who were treating the sickest Covid-19 patients, many without proper protective gear – died at a rate of 30 per 100,000 men, as a whole. The rate among ambulance staff (82.4) was still higher, however. 

The ONS – who cautioned there was not enough data to accurately look at the most dangerous jobs for women – says its data does not prove these jobs are more dangerous than working in hospitals because it does not take into account ethnicity or deprivation, two factors linked to a higher risk of dying.

And statisticians warned the rate for factory and security workers will also be skewed upwards because there are many more healthcare workers. For example, 130 male healthcare workers died from coronavirus during the two-and-a-half month period, compared to 62 deaths among factory employees.

Factory workers have worked throughout the crisis to keep the nation fed during lockdown, and are among the most likely to have been interacting with others when the disease was spreading at its fastest. Security guards had to be deployed to supermarkets during the outbreak to ensure social distancing was adhered to inside shops and in queues, exposing them to hundreds of potential Covid-19 carriers each day.

Data also shows the death rate was higher in 17 different occupations for men, including taxi drivers (65), chefs (56.8), busmen (44.2) and shop assistants (34.2) at a higher rate than the national average (19.1). They were up to six times more likely to die from Covid than men in ‘professional’ occupations (11.1 per 100,000). This is largely thought to be because they continue to work from home and avoid contact with others. 

Experts said today’s findings showed that Covid-19 ‘is largely an occupational disease’ and called for all workers who have regular contact with patients or the public to be supplied with personal protective equipment (PPE).  

For this reason, ‘the UK operational false positive rate is unknown’, the experts said, and ‘there are no published studies on the operational false positive rate of any national COVID-19 testing programme.’

They used a model which combined results from seven studies and more than 1,300 swab tests to create a model of the the false negative rate for the test.

The model suggested that in the first four days of infection, when a patient is pre-symptomatic, the tests can give a false positive up to 67 per cent of the time. 

This is because the virus has not yet had time to duplicate inside their respiratory system, making it hard to pick up by the test.

The chance of a false negative then dropped to 38 per cent on day 5 – the day when most people get symptoms. 

By day eight, the tests were 80 per cent accurate, meaning they gave a false negative one in five times to people who had symptoms for at least three days.  

The researchers recommended the Government launches an independent quality assessment review of the testing programme to make sure its fit for purpose.

They also said negative results that allow people to return to work, leave hospital or come out of isolation should be ‘treated with extreme caution’.

These people should self-isolate for 14 days regardless of the test result, the experts advised. 

Reacting to the SAGE paper, Professor Rowland Kao, an epidemiologist at the University of Edinburgh, said: ‘The report that up to 20 per cent of PCR tests may be falsely negative reflects the many operational challenges associated with correctly doing the test ranging from the initial collection of the sample, through to potential issues with storing or transferring the sample taken, or the laboratory procedures to interpret the sample. 

‘It’s important to remember that the test does not have to be perfect in order to be an effective component of disease control. All that is necessary is that the combination of measures taken have to be sufficient to keep the R number below one. Therefore maintaining those other measures, including social distancing and self-isolation, remain important even if with an extensive testing capability.’

More than half of Brits ignored PM’s plea to avoid pubs and bars

Boris Johnson’s plea for Britons to stay away from pubs, bars and restaurants in mid-March fell on deaf ears, a poll submitted to SAGE revealed.

A YouGov survey between March 17 and 18, a week before lockdown, showed more than half (55 per cent) of adults were still eating and drinking out.

Forty-five per cent said they’d stopped altogether and 17 per cent said they’d reduced the amount of times they attended the establishments.

Mr Johnson was adamant not to put the UK into lockdown, as the rest of Europe had at the time, and instead tried to use public messaging on social distancing and hand washing in early March to curb the spread.

But the YouGov poll, along with alarming predictions that hundreds of thousands of people would die from the virus, forced him to impose the nationwide quarantine. 

The survey also found that just 27 per cent of people stopped seeing family from other households. 

Just over a third (35 per cent) of the public, and more than half (59 per cent) of full-time workers were still going to work as often as before.

Only 16 per cent of children had stopped going to school by March 18. 

Extra attention must be paid to homeless hostels, migrant centres and mental health institutions, where Covid-19 could run rampant

A University College London paper submitted in late May warned the Government that there were several institutional settings at high risk of suffering clusters of infections.

The team said that, as well as hospitals and care homes, cruise ships, prisons, homeless shelters, migrant centres, factories and long-stay mental health facilities were vulnerable. 

This is because they are enclosed institutions which act as ‘reservoirs of infection’, house vulnerable individiuals and often include individuals who are less inclined to seek treatment or find it difficult to access healthcare (such as the homeless and migrants).

The report offered one piece of evidence – drawing on data from the US, France and UK which suggested homeless shelters housed up to a third of residents with Covid and up to 15 per cent of staff with the disease.

But the report was primarily a warning based on other reports. The researchers said it was important these ‘forgotten institutions’ were provided with adequate PPE, clear social distancing instructions and that more surveillance studies be launched into them. 

On May 28, SAGE used the UCL report to advise the Government ‘strongly’ that identifiying these high risk areas and implementing preventative measures in these places must be ‘proactive’.

Brits in high-risk jobs must be made aware of the threat of Covid 

SAGE urged the Government to raise awareness about the risk of catching Covid for people in certain jobs.

Office for National Statistics figures have shown that shop assistants, taxi drivers, factory workers and other public-facing workers are being disproportionately killed by Covid. 

Scientists said these people should be targeted through public health messaging, telling them to ‘pay particularly close attention to the social distancing and hygiene recommendations ‘.

Men working in so-called 'elementary occupations' were the worst-hit group during the height of the coronavirus outbreak in Britain. These workers are mostly in public-facing jobs and are least likely to have been able to work from home. Whereas men in 'professional' occupations had the lowest death rate, largely thought to be because they continue to work home and avoid contact with others

Men working in so-called ‘elementary occupations’ were the worst-hit group during the height of the coronavirus outbreak in Britain. These workers are mostly in public-facing jobs and are least likely to have been able to work from home. Whereas men in ‘professional’ occupations had the lowest death rate, largely thought to be because they continue to work home and avoid contact with others

It is vital that the responsibility for managing infection risk due to multiple contacts is shared between the people at risk and their employers, SAGE said.

Wherever possible, changes to the structuring of workplace activities and environments should be prioritised, they said.

This would include ‘taking extra care to manage infection risk may also involve everyone concerned undertaking additional actions such as handwashing at appropriate times, avoiding touching face or surfaces, cleaning all shared surfaces, changing/washing clothes, using and disposing of tissues, ventilating shared spaces, social distancing, wearing a face covering when close to others if social distancing is not possible’. 

Ministers must tailor health messages to people from BAME groups

The Government has been told that coronavirus health messages tailored specifically for different ethnic groups are ‘particularly important’. 

Ministers were recommended to give people from BAME backgrounds – who are disproportionately affected by the virus – extra advice on how to stay safe during the crisis. 

The advice is outlined in a summary of a discussion on ethnicity and Covid-19 risk, endorsed SAGE on June 4.  

The Sage summary said: ‘Work was discussed that highlighted the importance of faith practices, differences in patterns of healthcare usage, willingness of communities to engage with prevention, and other factors such as access to outdoor space. 

‘Different messaging, including health messages tailored specifically for different ethnic groups was highlighted as being particularly important.’  

Two reports have been published by Public Health England (PHE) in recent weeks which suggested BAME communities are dying from Covid-19 at greater rates than people in white ethnic groups. 

The earlier findings from PHE said that people of Bangladeshi heritage were dying at around twice the rate of white Britons. 

It also found that other minority ethnic groups were at up to 50 per cent higher risk of dying. 

The second report pointed to a raft of recommendations from stakeholders, including the need to develop ‘occupational risk assessment tools that can be employed in a variety of occupational settings and used to reduce the risk of employee’s exposure to and acquisition of Covid-19’.

This is especially true for BAME workers in health and social care and on the front line in occupations that put them at higher risk, it said.

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Written by Angle News

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